Research Articles
Measuring the Unseen: Advanced Techniques and Best Practices for Aerosol Transmission Analysis in Biomedical Research
This comprehensive guide for researchers, scientists, and drug development professionals details the evolving landscape of aerosol transmission measurement.
Decoding the SARS-CoV-2 Genome: A Comprehensive Guide to Diagnostic Protein Targets and Assay Development
This article provides a comprehensive technical overview of the SARS-CoV-2 genome structure and its encoded proteins, with a focused analysis on their application in molecular and antigen-based diagnostics.
Nasal vs. Nasopharyngeal Swabs for SARS-CoV-2 Detection: A Comprehensive Analysis of Diagnostic Sensitivity
This article provides a systematic review and analysis for researchers and diagnostics professionals comparing the analytical and clinical sensitivity of nasal (anterior nares/mid-turbinate) and nasopharyngeal (NP) swabs for detecting SARS-CoV-2.
Decoding Viral Pathogenesis: A Comprehensive Guide to Characterizing SARS-CoV-2 Cytopathic Effects In Vitro
This article provides a detailed methodological and analytical framework for researchers characterizing the cytopathic effects (CPE) of SARS-CoV-2 in vitro.
Analyzing SARS-CoV-2 Antigen Test Performance in Asymptomatic Populations: A Critical Review for Researchers and Drug Developers
This article provides a comprehensive review and analysis of SARS-CoV-2 rapid antigen test (RAT) performance in asymptomatic individuals, a critical area for public health and pharmaceutical strategy.
Correlating SARS-CoV-2 Antigen Rapid Test Results with Viral Culture: A Critical Analysis for Research and Development
This article provides a comprehensive overview of SARS-CoV-2 Antigen Rapid Diagnostic Test (Ag-RDT) correlation studies with the gold-standard of cell culture infectivity.
Beyond the Sequence: How Metadata Quality Defines Viral Database Accuracy and Impacts Biomedical Research
For researchers and drug development professionals, viral databases are foundational tools.
Benchmarking Viral Phylogenies: A Practical Guide to Robinson-Foulds Distance for Method Comparison in Research and Drug Development
This article provides a comprehensive guide for researchers and biomedical professionals on utilizing the Robinson-Foulds (RF) distance metric to compare and validate phylogenetic tree inference methods for viral genomic data.
From 'Unclassified' to Identified: Solving Taxonomic Labelling Errors in Biomedical Databases for Drug Development
This article addresses the critical challenge of unspecific and erroneous taxonomic labelling in genomic, metagenomic, and microbiome databases, a pervasive issue that undermines reproducibility and translational research.
Strategic Guide to Reducing False Positives in Metagenomic Virus Detection: Methods, Validation, and Clinical Impact
This article provides a comprehensive guide for researchers and bioinformaticians tackling the pervasive challenge of false positives in metagenomic virus detection.